C57BL/6N-Hp1bp3^{tm1a(EUCOMM)Wtsi}Tg(Vil1-cre)997Gum/H

Status	Available to order
EMMA ID	EM:15867
Citation information	RRID:IMSR_EM:15867 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.
International strain name	C57BL/6N-Hp1bp3^{tm1a(EUCOMM)Wtsi}Tg(Vil1-cre)997Gum/H
Alternative name	hp1bp3 x Villin-Cre
Strain type	Targeted Mutant Strains
Allele/Transgene symbol	Hp1bp3^{tm1c(EUCOMM)Wtsi}, Tg(Vil1-cre)20Syr
Gene/Transgene symbol	Hp1bp3, Tg(Vil1-cre)20Syr

Information from provider

Provider	Abdol Shams-Nateri
Provider affiliation	School of Medicine, University of Nottingham
Genetic information	Hp1bp3 knockout targeted to intestinal epithelium
Phenotypic information	Homozygous: Normal Heterozygous: Normal
Breeding history	- Provided to EMMA from Wellcome Trust Sanger Institute - Logged as EMMA as #05382 (https://www.infrafrontier.eu/strain-search/straindetails/?q=5382) - Full nomenclature: B6Brd;B6N-Tyrc-Brd Hp1bp3^{tm1a(EUCOMM)Wtsi}/WtsiCnbc - Converted to a conditional mutant (TM1C) by exposure to FLP recombinase. - Mice bred with Tg(Vil1-cre)20Syr (JAX033019) to target mutation to intestinal epithelium - Then bred as homozygotes
References	None available
Homozygous fertile	yes
Homozygous viable	yes
Homozygous matings required	no
Immunocompromised	no

Information from EMMA

Archiving centre	Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

MGI phenotypes (gene matching)

decreased body weight / MGI
postnatal growth retardation / MGI
homeostasis/metabolism phenotype / MGI
cellular phenotype / MGI
decreased birth weight / MGI
postnatal lethality, incomplete penetrance / MGI

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Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*
Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

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Practical information

Example health report
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Material Transfer Agreement (MTA)
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Legally binding conditions for the transfer

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C57BL/6N-Hp1bp3tm1a(EUCOMM)WtsiTg(Vil1-cre)997Gum/H