IMPC phenotypes (gene matching)
FVB-Trim66em1Emr/Cnrm
| Status | Under development - register interest |
| EMMA ID | EM:15904 |
| Citation information | RRID:IMSR_EM:15904 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | FVB-Trim66em1Emr/Cnrm |
| Alternative name | Trim66 em2(gfp) |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Trim66em1Emr |
| Gene/Transgene symbol | Trim66 |
Information from provider
| Provider | Matthieu Boulard |
| Provider affiliation | EMBL Rome, European Molecular Biology Laboratory |
| Genetic information | Insertion in frame in exon 3 of transcript Trim66-201 (Ensembl v91) of a cassette including eGfp, stop codon, and SV40 poly-A signal. The genomic coordinate of the insertion is Chr 7. 109,083,675 (GRCm39/mm39). |
| Phenotypic information | Homozygous:No adverse phenotype was observed. Homozygous animals are healthy and fertile.Heterozygous:No adverse phenotype was observed. Homozygous animals are healthy and fertile. |
| Breeding history | Breeding of heterozygotes with FVB animals. |
| References |
|
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Literature references
- Trim66's paternal deficiency causes intrauterine overgrowth.;Mielnicka Monika, Tabaro Francesco, Sureka Rahul, Acurzio Basilia, Paoletti Renata, Scavizzi Ferdinando, Raspa Marcello, Crevenna Alvaro H, Lapouge Karine, Remans Kim, Boulard Matthieu, ;2024;Life science alliance;7;; 38719749