IMPC phenotypes (gene matching)
- preweaning lethality, complete penetrance / IMPC
Fignl1tm1Ics/Ics
| Status | Available to order |
| EMMA ID | EM:16064 |
| Citation information | RRID:IMSR_EM:16064 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | Fignl1tm1Ics/Ics |
| Alternative name | Fignl1tm1Ics/Ics |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Fignl1tm1Ics |
| Gene/Transgene symbol | Fignl1 |
Information from provider
| Provider | Frédéric Baudat |
| Provider affiliation | CNRS, Institut de Génétique Humaine, UMR 9002, CNRS, Université de Montpellier |
| Genetic information | This allele was generated using the EUCOMM knock-out first with conditional potential contruct PG00241_Z_4_H09. |
| Phenotypic information | Homozygous:N/AHeterozygous:N/A |
| Breeding history | Pure C57BL/6N genetic background. Current background: C57BL/6N 12.5%, C57BL/6NCrl 87.4939%, C57BL/6NTac 0.006% |
| References |
|
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France |
Disease and phenotype information
Literature references
- FIGNL1-FIRRM is essential for meiotic recombination and prevents DNA damage-independent RAD51 and DMC1 loading.;Zainu Akbar, Dupaigne Pauline, Bouchouika Soumya, Cau Julien, Clément Julie A J, Auffret Pauline, Ropars Virginie, Charbonnier Jean-Baptiste, de Massy Bernard, Mercier Raphael, Kumar Rajeev, Baudat Frédéric, ;2024;Nature communications;15;7015; 39147779