IMPC phenotypes (allele matching)
- preweaning lethality, complete penetrance / IMPC
C57BL/6N-Slc17a6tm1b(EUCOMM)Hmgu/H
| Status | Only small colony available |
| EMMA ID | EM:16239 |
| Citation information | RRID:IMSR_EM:16239 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Slc17a6tm1b(EUCOMM)Hmgu/H |
| Alternative name | HEPD0629_3_H07 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Slc17a6tm1b(EUCOMM)Hmgu |
| Gene/Transgene symbol | Slc17a6 |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | Mary Lyon Centre at MRC Harwell |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This mouse line originates from EUCOMM ES clone HEPD0629_3_H07. For further details on the construction of this clone see the page at the IMPC portal. The critical exon(s) were flanked by loxP sites, and subsequent cre expression excised this critical sequence resulting in a knockout reporter allele. Click here for more information on EUCOMM final vectors. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
IMPC phenotypes (gene matching)
- preweaning lethality, complete penetrance / IMPC
MGI phenotypes (gene matching)
- hunched posture / MGI
- cyanosis / MGI
- respiratory failure / MGI
- abnormal reflex / MGI
- abnormal pain threshold / MGI
- abnormal motor capabilities/coordination/movement / MGI
- no abnormal phenotype detected / MGI
- abnormal CNS synaptic transmission / MGI
- abnormal conditioned taste aversion behavior / MGI
- abnormal excitatory postsynaptic currents / MGI
- no phenotypic analysis / MGI
- abnormal locomotor activation / MGI
- abnormal nervous system physiology / MGI
- abnormal synaptic vesicle morphology / MGI
- abnormal synaptic vesicle number / MGI
- enlarged third ventricle / MGI
- decreased fetal weight / MGI
- decreased birth body size / MGI
- abnormal pre-Botzinger complex physiology / MGI
- absence of AMPA-mediated synaptic currents / MGI
- postnatal lethality, complete penetrance / MGI
- neonatal lethality, complete penetrance / MGI