- increased neutrophil cell number / IMPC
- decreased locomotor activity / IMPC
- decreased hemoglobin content / IMPC
- decreased erythrocyte cell number / IMPC
- decreased lymphocyte cell number / IMPC
- impaired glucose tolerance / IMPC
- decreased circulating serum albumin level / IMPC
- increased red blood cell distribution width / IMPC
- decreased circulating fructosamine level / IMPC
- preweaning lethality, complete penetrance / IMPC
C57BL/6N-Commd9tm1b(KOMP)Wtsi/H
| Status | Only small colony available |
| EMMA ID | EM:16353 |
| Citation information | RRID:IMSR_EM:16353 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Commd9tm1b(KOMP)Wtsi/H |
| Alternative name | EPD0136_6_D11 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Commd9tm1b(KOMP)Wtsi |
| Gene/Transgene symbol | Commd9 |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | Mary Lyon Centre at MRC Harwell |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This mouse line originates from KOMP ES clone EPD0136_6_D11. For further details on the construction of this clone see the page at the IMPC portal. The critical exon(s) were flanked by loxP sites, and subsequent cre expression excised this critical sequence resulting in a knockout reporter allele. Click here for more information on KOMP final vectors. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- increased red blood cell distribution width / IMPC
- decreased locomotor activity / IMPC
- decreased hemoglobin content / IMPC
- decreased erythrocyte cell number / IMPC
- decreased circulating fructosamine level / IMPC
- decreased circulating serum albumin level / IMPC
- decreased lymphocyte cell number / IMPC
- preweaning lethality, complete penetrance / IMPC
- increased neutrophil cell number / IMPC
- impaired glucose tolerance / IMPC
MGI phenotypes (gene matching)
- abnormal cardiovascular system physiology / MGI
- edema / MGI
- hemorrhage / MGI
- intracranial hemorrhage / MGI
- intracerebral hemorrhage / MGI
- abnormal neural tube morphology / MGI
- abnormal vein morphology / MGI
- heart hypoplasia / MGI
- abnormal dorsal aorta morphology / MGI
- dilated vasculature / MGI
- hemopericardium / MGI
- myocardial necrosis / MGI
- embryonic lethality during organogenesis, complete penetrance / MGI
- abnormal cranial blood vasculature morphology / MGI
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