NOD.B6-Ptprcb/Orl
| Status | Available to order |
| EMMA ID | EM:01637 |
| International strain name | NOD.B6-Ptprcb/Orl |
| Alternative name | NOD.CD45.2 |
| Strain type | Spontaneous |
| Allele/Transgene symbol | Ptprcb, |
| Gene/Transgene symbol | Ptprc |
Information from provider
| Provider | Francoise Lepault |
| Provider affiliation | INSERM U561 - Hopital Saint Vincent de Paul |
| Genetic information | NOD congenic strain for Ptprcb (CD45.2) from C57BL/6. |
| Phenotypic information | No phenotypic changes detected. Diabetes incidence similar to wild-type NOD mice. |
| Breeding history | NOD mice were crossed with C57BL/6 mice and backcrossed to the NOD background for more than 10 times, before brother-sister intercross. Mice are homozygous for Ptprcb (CD45.2). No breeding problem with this line. |
| References | None available |
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- T-B+ severe combined immunodeficiency due to CD45 deficiency / Orphanet_169157