- abnormal gait / IMPC
- abnormal vocalization / IMPC
- decreased mean corpuscular volume / IMPC
- decreased hemoglobin content / IMPC
- increased erythrocyte cell number / IMPC
- decreased mean corpuscular hemoglobin / IMPC
- increased red blood cell distribution width / IMPC
- preweaning lethality, complete penetrance / IMPC
- embryonic lethality prior to tooth bud stage / IMPC
C57BL/6NTac-Tfrcem1(IMPC)H/H
| Status | Only small colony available |
| EMMA ID | EM:16419 |
| Citation information | RRID:IMSR_EM:16419 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6NTac-Tfrcem1(IMPC)H/H |
| Alternative name | |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Tfrcem1(IMPC)H |
| Gene/Transgene symbol | Tfrc |
Information from provider
| Provider | Mary Lyon Centre at MRC Harwell |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Combined immunodeficiency due to TFRC deficiency / Orphanet_476113
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- increased red blood cell distribution width / IMPC
- decreased mean corpuscular hemoglobin / IMPC
- abnormal gait / IMPC
- preweaning lethality, complete penetrance / IMPC
- decreased mean corpuscular volume / IMPC
- increased erythrocyte cell number / IMPC
- abnormal vocalization / IMPC
- embryonic lethality prior to tooth bud stage / IMPC
- decreased hemoglobin content / IMPC
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