C57BL/6NTac-Grm5em1(IMPC)H/H

Status

Only small colony available

EMMA IDEM:16433
Citation informationRRID:IMSR_EM:16433 

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International strain nameC57BL/6NTac-Grm5em1(IMPC)H/H
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolGrm5em1(IMPC)H
Gene/Transgene symbolGrm5

Information from provider

Provider Mary Lyon Centre at MRC Harwell
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

MGI phenotypes (gene matching)
  • decreased body weight / MGI
  • abnormal cued conditioning behavior / MGI
  • abnormal spatial learning / MGI
  • abnormal contextual conditioning behavior / MGI
  • reduced long term potentiation / MGI
  • abnormal motor coordination/balance / MGI
  • increased thermal nociceptive threshold / MGI
  • abnormal cocaine consumption / MGI
  • abnormal nociception after inflammation / MGI
  • decreased susceptibility to pharmacologically induced seizures / MGI
  • increased susceptibility to pharmacologically induced seizures / MGI
  • abnormal excitatory postsynaptic potential / MGI
  • abnormal locomotor activation / MGI
  • abnormal nerve fiber response / MGI
  • decreased alcohol consumption / MGI
  • behavior/neurological phenotype / MGI
  • abnormal latent inhibition of conditioning behavior / MGI
  • impaired behavioral response to cocaine / MGI
  • decreased total body fat amount / MGI
  • abnormal inhibitory learning / MGI

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Order (limited)

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
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