C57BL/6NTac-Npr2em1(IMPC)H/H

Status

Only small colony available

EMMA IDEM:16435
Citation informationRRID:IMSR_EM:16435 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NTac-Npr2em1(IMPC)H/H
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolNpr2em1(IMPC)H
Gene/Transgene symbolNpr2

Information from provider

Provider Mary Lyon Centre at MRC Harwell
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

IMPC phenotypes (allele matching)
  • abnormal head morphology / IMPC
  • abnormal snout morphology / IMPC
  • abnormal forelimb morphology / IMPC
  • abnormal hindlimb morphology / IMPC
  • tremors / IMPC
  • abnormal locomotor behavior / IMPC
  • abnormal gait / IMPC
  • trunk curl / IMPC
  • limb grasping / IMPC
  • abnormal tail morphology / IMPC
  • decreased circulating alkaline phosphatase level / IMPC
  • impaired cued conditioning behavior / IMPC
  • increased grip strength / IMPC
  • preweaning lethality, incomplete penetrance / IMPC
  • abnormal head size / IMPC
  • abnormal tail length / IMPC
  • increased freezing behavior / IMPC
IMPC phenotypes (gene matching)
  • abnormal hindlimb morphology / IMPC
  • abnormal tail morphology / IMPC
  • abnormal tail length / IMPC
  • abnormal forelimb morphology / IMPC
  • abnormal snout morphology / IMPC
  • decreased circulating alkaline phosphatase level / IMPC
  • increased freezing behavior / IMPC
  • abnormal head morphology / IMPC
  • preweaning lethality, incomplete penetrance / IMPC
  • trunk curl / IMPC
  • impaired cued conditioning behavior / IMPC
  • limb grasping / IMPC
  • tremors / IMPC
  • abnormal head size / IMPC
  • increased grip strength / IMPC
  • abnormal gait / IMPC
  • abnormal locomotor behavior / IMPC

Information on how we integrate external resources can be found here

Order (limited)

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
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