C57BL/6NTac-Mchr1em1(IMPC)H/H

Status

Only small colony available

EMMA IDEM:16492
Citation informationRRID:IMSR_EM:16492 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NTac-Mchr1em1(IMPC)H/H
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolMchr1em1(IMPC)H
Gene/Transgene symbolMchr1

Information from provider

Provider Mary Lyon Centre at MRC Harwell
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

MGI phenotypes (gene matching)
  • osteoporosis / MGI
  • decreased body weight / MGI
  • weight loss / MGI
  • abnormal social investigation / MGI
  • decreased anxiety-related response / MGI
  • hyperactivity / MGI
  • polyphagia / MGI
  • abnormal sleep pattern / MGI
  • increased circulating corticosterone level / MGI
  • abnormal nervous system electrophysiology / MGI
  • increased heart rate / MGI
  • decreased circulating insulin level / MGI
  • abnormal passive avoidance behavior / MGI
  • abnormal frequency of paradoxical sleep / MGI
  • abnormal hormone level / MGI
  • increased lean body mass / MGI
  • abnormal metabolism / MGI
  • homeostasis/metabolism phenotype / MGI
  • abnormal energy expenditure / MGI
  • decreased percent body fat/body weight / MGI
  • decreased thyroxine level / MGI
  • increased body temperature / MGI
  • decreased susceptibility to diet-induced obesity / MGI
  • decreased circulating leptin level / MGI
  • slow postnatal weight gain / MGI
  • impaired behavioral response to xenobiotic / MGI
  • decreased total body fat amount / MGI
  • decreased serotonin level / MGI
  • decreased response to stress-induced hyperthermia / MGI
  • decreased respiratory quotient / MGI
  • abnormal circadian temperature homeostasis / MGI
  • increased food intake / MGI
  • increased fluid intake / MGI

Information on how we integrate external resources can be found here

Order (limited)

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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