C57BL/6NCrl-Snap25em1(IMPC)Ccpcz/Ph

Status

Under development - register interest

EMMA IDEM:16682
Citation informationRRID:IMSR_EM:16682 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameC57BL/6NCrl-Snap25em1(IMPC)Ccpcz/Ph
Alternative name
Strain typeEndonuclease-mediated
Allele/Transgene symbolSnap25em1(IMPC)Ccpcz
Gene/Transgene symbolSnap25

Information from provider

Provider Institute of Molecular Genetics
Provider affiliationDepartment of Transgenic Models of Diseases, Institute of Molecular Genetics
Genetic informationThis mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal.
Phenotypic informationPotential phenotyping data in the IMPC portal
ReferencesNone available

Information from EMMA

Archiving centreInstitute of Molecular Genetics, Prague, Czech Republic

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (gene matching)
  • increased white adipose tissue amount / MGI
  • myoclonus / MGI
  • tremors / MGI
  • thin diaphragm muscle / MGI
  • abnormal cerebral cortex morphology / MGI
  • convulsive seizures / MGI
  • abnormal skin condition / MGI
  • increased body weight / MGI
  • decreased body weight / MGI
  • decreased body size / MGI
  • delayed eyelid opening / MGI
  • increased anxiety-related response / MGI
  • abnormal locomotor behavior / MGI
  • ataxia / MGI
  • hyperactivity / MGI
  • hypoactivity / MGI
  • no spontaneous movement / MGI
  • impaired coordination / MGI
  • abnormal object recognition memory / MGI
  • abnormal spatial learning / MGI
  • unresponsive to tactile stimuli / MGI
  • disheveled coat / MGI
  • increased circulating triglyceride level / MGI
  • hyperglycemia / MGI
  • abnormal blood vessel morphology / MGI
  • decreased embryo size / MGI
  • abnormal dopamine level / MGI
  • infertility / MGI
  • respiratory failure / MGI
  • seizures / MGI
  • abnormal motor capabilities/coordination/movement / MGI
  • increased circulating insulin level / MGI
  • premature death / MGI
  • abnormal brain morphology / MGI
  • no abnormal phenotype detected / MGI
  • abnormal CNS synaptic transmission / MGI
  • abnormal intercostal muscle morphology / MGI
  • hepatic steatosis / MGI
  • akinesia / MGI
  • decreased glucagon secretion / MGI
  • decreased vertical activity / MGI
  • increased thigmotaxis / MGI
  • blotchy skin / MGI
  • abnormal PNS synaptic transmission / MGI
  • abnormal endplate potential / MGI
  • enhanced paired-pulse facilitation / MGI
  • decreased paired-pulse facilitation / MGI
  • no phenotypic analysis / MGI
  • decreased insulin secretion / MGI
  • decreased width of hypertrophic chondrocyte zone / MGI
  • abnormal pancreatic beta cell physiology / MGI
  • abnormal insulin secretion / MGI
  • decreased synaptic glutamate release / MGI
  • abnormal miniature excitatory postsynaptic currents / MGI
  • increased circulating cholesterol level / MGI
  • improved glucose tolerance / MGI
  • abnormal serotonin level / MGI
  • insulin resistance / MGI
  • behavior/neurological phenotype / MGI
  • taste/olfaction phenotype / MGI
  • increased susceptibility to diet-induced obesity / MGI
  • increased circulating leptin level / MGI
  • increased body mass index / MGI
  • impaired hearing / MGI
  • abnormal hippocampus CA3 region morphology / MGI
  • increased white fat cell size / MGI
  • decreased prepulse inhibition / MGI
  • abnormal impulsive behavior control / MGI
  • postnatal lethality, incomplete penetrance / MGI
  • neonatal lethality, complete penetrance / MGI
  • decreased circulating ghrelin level / MGI
  • increased food intake / MGI
  • decreased food intake / MGI

Information on how we integrate external resources can be found here

Register interest

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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