MGI phenotypes (gene matching)
- no abnormal phenotype detected / MGI
B6.129X1-Npdc1tm1Ce/Orl
| Status | Under development - register interest |
| EMMA ID | EM:16735 |
| Citation information | RRID:IMSR_EM:16735 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129X1-Npdc1tm1Ce/Orl |
| Alternative name | C57BL/6J-Npdc1tm1Ce |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Npdc1tm1Ce |
| Gene/Transgene symbol | Npdc1 |
Information from provider
| Provider | Thierry Heidmann |
| Provider affiliation | GUSTAVE ROUSSY |
| Genetic information | Knock-out of Npdc1 gene. This strain was obtained by backcrossing the B6;129X1-Npdc1tm1Ce/Orl strain (EMMA strain ID EM:00211) with C57BL/6J wild-type mice. The original B6;129X1-Npdc1tm1Ce/Orl mutant mice were generated by gene targeting in 129/SvJ ES cells. The genomic sequence (Genbank AF263513) was interrupted by the pGN plasmid sequence. This plasmid includes the lacZ gene and the neoR gene without polyadenylation sites. |
| Phenotypic information | Homozygous:no abnormal phenotype detectedHeterozygous:no abnormal phenotype detected |
| Breeding history | This strain was obtained by backcrossing the B6;129X1-Npdc1tm1Ce/Orl strain (EM:00211) with C57BL/6J wild-type mice. The original B6;129X1-Npdc1tm1Ce/Orl mutant mice were generated by gene targeting in 129/SvJ ES cells. The genomic sequence (Genbank AF263513) was interrupted by the pGN plasmid sequence. This plasmid includes the lacZ gene and the neoR gene without polyadenylation sites. Number of backcrosses: 10+ |
| References | None available |
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |
| Animals used for archiving | heterozygous C57BL/6J males |