STOCK Yod1tm1bNarlH

Status

Under development - register interest

EMMA IDEM:16767
Citation informationRRID:IMSR_EM:16767 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

International strain nameSTOCK Yod1tm1bNarlH
Alternative nameSTOCK Yod1H
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolYod1tm1bNarl
Gene/Transgene symbolYod1

Information from provider

Provider MRC, Medical Research Council
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationA conditional allele with an FRT-flanked neomycin resistance cassette. Cre-mediated recombination removed the floxed gene segment and the selection cassette.
Phenotypic informationHomozygous:
These mice are part of the International Mouse Phenotyping Consortium (IMPC) and will be phenotyped through a standardised phenotyping pipeline. Details of the pipeline and data, when available, can be viewed at www.mousephenotype.org

Heterozygous:
These mice are part of the International Mouse Phenotyping Consortium (IMPC) and will be phenotyped through a standardised phenotyping pipeline. Details of the pipeline and data, when available, can be viewed at www.mousephenotype.org
Breeding historyThe tm1a mice were imported on n undefined C57BL/6 background. The strain has since been converted to a tm1b and maintained on a C57BL/6NTac USA background
ReferencesNone available
Homozygous fertileyes
Homozygous viableyes
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

IMPC phenotypes (allele matching)
  • increased neutrophil cell number / IMPC
  • increased circulating alanine transaminase level / IMPC
  • decreased lymphocyte cell number / IMPC
  • increased circulating aspartate transaminase level / IMPC
IMPC phenotypes (gene matching)
  • increased neutrophil cell number / IMPC
  • increased circulating aspartate transaminase level / IMPC
  • increased circulating alanine transaminase level / IMPC
  • decreased lymphocyte cell number / IMPC

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Register interest

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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