IMPC phenotypes (gene matching)
C57BL/6N-Atm1BrdH13tm1c(KOMP)Wtsi/WtsiH
| Status | Available to order |
| EMMA ID | EM:16773 |
| Citation information | RRID:IMSR_EM:16773 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Atm1BrdH13tm1c(KOMP)Wtsi/WtsiH |
| Alternative name | C57BL/6N-A |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | H13 |
| Gene/Transgene symbol | H13 |
Information from provider
| Provider | MRC, Medical Research Council |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | The L1L2_Bact_P cassette was inserted at position 152522482 of Chromosome 2 upstream of exon 3(Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 3 at position 152523314. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exon 3 floxed. |
| Phenotypic information | Homozygous:These mice are part of the International Mouse Phenotyping Consortium (IMPC) and will be phenotyped through a standardised phenotyping pipeline. Details of the pipeline and data, when available, can be viewed at www.mousephenotype.orgHeterozygous:These mice are part of the International Mouse Phenotyping Consortium (IMPC) and will be phenotyped through a standardised phenotyping pipeline. Details of the pipeline and data, when available, can be viewed at www.mousephenotype.org |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI phenotypes (gene matching)
- abnormal vertebrae morphology / MGI
- abnormal rib morphology / MGI
- absent ribs / MGI
- abnormal interatrial septum morphology / MGI
- double outlet right ventricle / MGI
- absent kidney / MGI
- enlarged liver sinusoidal spaces / MGI
- abnormal forebrain morphology / MGI
- abnormal olfactory bulb morphology / MGI
- abnormal hindbrain morphology / MGI
- exencephaly / MGI
- fused dorsal root ganglion / MGI
- absent superior cervical ganglion / MGI
- small superior cervical ganglion / MGI
- abnormal tail morphology / MGI
- abnormal brain morphology / MGI
- abnormal outer ear morphology / MGI
- situs inversus / MGI
- abnormal posterior semicircular canal morphology / MGI
- small thyroid gland / MGI
- small kidney / MGI
- left pulmonary isomerism / MGI
- abnormal forebrain development / MGI
- abnormal nervous system morphology / MGI
- abnormal eye muscle morphology / MGI
- abnormal Mullerian duct morphology / MGI
- abnormal Wolffian duct morphology / MGI
- transposition of great arteries / MGI
- retroesophageal right subclavian artery / MGI
- abnormal optic stalk morphology / MGI
- abnormal optic cup morphology / MGI
- abnormal vertebral arch morphology / MGI
- abnormal cervical atlas morphology / MGI
- abnormal stapedial artery morphology / MGI
- absent stapedial artery / MGI
- decreased length of long bones / MGI
- absent Mullerian ducts / MGI
- abnormal styloid process morphology / MGI
- abnormal brain internal capsule morphology / MGI
- thoracoschisis / MGI
- abnormal optic chiasm morphology / MGI
- abnormal liver vasculature morphology / MGI
- perimembraneous ventricular septal defect / MGI
- muscular ventricular septal defect / MGI
- abnormal hepatic vein morphology / MGI
- abnormal inferior vena cava valve morphology / MGI
- abnormal pulmonary valve cusp morphology / MGI
- abnormal hypoglossal canal morphology / MGI
- absent hypoglossal canal / MGI
- thin hypoglossal nerve / MGI
- absent hypoglossal nerve / MGI
- abnormal hypoglossal nerve topology / MGI
- absent segment of posterior cerebral artery / MGI
- subcutaneous edema / MGI
- absent celiac artery / MGI
- abnormal azygos vein topology / MGI
- abnormal vitelline vein connection / MGI
- abnormal pancreas topology / MGI
- enlarged paraumbilical vein / MGI
- abnormal stapedial artery topology / MGI
- absent ductus venosus valve / MGI
- abnormal ductus venosus valve morphology / MGI
- abnormal brachial plexus formation / MGI
- abnormal thymus topology / MGI
- abnormal infrahyoid muscle morphology / MGI
- abnormal infrahyoid muscle connection / MGI
- multiple persisting craniopharyngeal ducts / MGI
- reduced sympathetic cervical ganglion size / MGI
- blood in lymph vessels / MGI
- symmetric azygos veins / MGI
- abnormal umbilical vein topology / MGI
- abnormal vitelline vein topology / MGI
- persistent dorsal ophthalmic artery / MGI
- abnormal vertebral artery origin / MGI
- absent posterior communicating artery / MGI
- embryo tumor / MGI
- heterochrony / MGI
- abnormal intestine placement / MGI
- absent inferior vena cava / MGI