C57BL/6N-Tgm1^{tm1b(EUCOMM)Hmgu}/H

Status	Under development - register interest
EMMA ID	EM:16779
Citation information	RRID:IMSR_EM:16779 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.
International strain name	C57BL/6N-Tgm1^{tm1b(EUCOMM)Hmgu}/H
Alternative name	C57BL/6N-Tgm1/H
Strain type	Targeted Mutant Strains : Knock-out
Allele/Transgene symbol	Tgm1^{tm1b(EUCOMM)Hmgu}
Gene/Transgene symbol	Tgm1

Information from provider

Provider	MRC, Medical Research Council
Provider affiliation	Mary Lyon Centre at MRC Harwell
Genetic information	This mouse line originates from ESC clone HEPD0652_1_E10. The critical exon(s) were flanked by loxP sites, and subsequent cre expression excised this critical sequence resulting in a knockout reporter allele . For further details on the construction of this clone see the page at the IMPC portal
Phenotypic information	Homozygous: These mice are part of the International Mouse Phenotyping Consortium (IMPC) and will be phenotyped through a standardised phenotyping pipeline. Details of the pipeline and data, when available, can be viewed at www.mousephenotype.org Heterozygous: These mice are part of the International Mouse Phenotyping Consortium (IMPC) and will be phenotyped through a standardised phenotyping pipeline. Details of the pipeline and data, when available, can be viewed at www.mousephenotype.org
References	None available
Homozygous fertile	not known
Homozygous viable	not known
Homozygous matings required	not known
Immunocompromised	not known

Information from EMMA

Archiving centre	Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

Congenital non-bullous ichthyosiform erythroderma / Orphanet_79394
Self-improving collodion baby / Orphanet_281122
Lamellar ichthyosis / Orphanet_313
Acral self-healing collodion baby / Orphanet_281127
Bathing suit ichthyosis / Orphanet_100976

Information on how we integrate external resources can be found here

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
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Legally binding conditions for the transfer

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C57BL/6N-Tgm1tm1b(EUCOMM)Hmgu/H