C57BL/6N-Atf3tm2c(EUCOMM)Wtsi/H

Status

Available to order

EMMA IDEM:16797
Citation informationRRID:IMSR_EM:16797 

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International strain nameC57BL/6N-Atf3tm2c(EUCOMM)Wtsi/H
Alternative nameC57BL/6N-Atf3/H
Strain typeTargeted Mutant Strains : Conditional mutation
Allele/Transgene symbolAtf3tm2c(EUCOMM)Wtsi
Gene/Transgene symbolAtf3

Information from provider

Provider MRC, Medical Research Council
Provider affiliationMary Lyon Centre at MRC Harwell
Genetic informationThis line originates from ESC clone EPD0537_5_G02, after breeding with a Flp recombinase deleter line to convert the original targeted allele tm1a (knock-out first allele) into a conditional allele tm1c. For further details on the construction of this clone see the page at the IMPC portal.
Phenotypic informationHomozygous:
These mice are part of the International Mouse Phenotyping Consortium (IMPC) and will be phenotyped through a standardised phenotyping pipeline. Details of the pipeline and data, when available, can be viewed at www.mousephenotype.org

Heterozygous:
These mice are part of the International Mouse Phenotyping Consortium (IMPC) and will be phenotyped through a standardised phenotyping pipeline. Details of the pipeline and data, when available, can be viewed at www.mousephenotype.org
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

IMPC phenotypes (gene matching)
  • abnormal retina morphology / IMPC
  • decreased locomotor activity / IMPC
MGI phenotypes (gene matching)
  • decreased metastatic potential / MGI
  • lung inflammation / MGI
  • neoplasm / MGI
  • no phenotypic analysis / MGI
  • abnormal pancreatic islet morphology / MGI
  • abnormal T-helper 2 physiology / MGI
  • decreased IgG2a level / MGI
  • increased interleukin-13 secretion / MGI
  • increased interleukin-4 secretion / MGI
  • increased interleukin-5 secretion / MGI

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Practical information

Genotyping protocol

Example health report
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