IMPC phenotypes (allele matching)
- increased spleen weight / IMPC
C57BL/6N-Selltm1b(EUCOMM)Hmgu/H
| Status | Only small colony available |
| EMMA ID | EM:16893 |
| Citation information | RRID:IMSR_EM:16893 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Selltm1b(EUCOMM)Hmgu/H |
| Alternative name | HEPD0551_6_A10 |
| Strain type | Targeted Mutant Strains |
| Allele/Transgene symbol | Selltm1b(EUCOMM)Hmgu |
| Gene/Transgene symbol | Sell |
| Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
| Provider | Mary Lyon Centre at MRC Harwell |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This mouse line originates from EUCOMM ES clone HEPD0551_6_A10. For further details on the construction of this clone see the page at the IMPC portal. The critical exon(s) were flanked by loxP sites, and subsequent cre expression excised this critical sequence resulting in a knockout reporter allele. Click here for more information on EUCOMM final vectors. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
IMPC phenotypes (gene matching)
- increased spleen weight / IMPC
MGI phenotypes (gene matching)
- increased monocyte cell number / MGI
- decreased monocyte cell number / MGI
- extramedullary hematopoiesis / MGI
- enlarged spleen / MGI
- spleen hyperplasia / MGI
- decreased metastatic potential / MGI
- decreased activated T cell number / MGI
- pancreas inflammation / MGI
- decreased tumor incidence / MGI
- abnormal hypersensitivity reaction / MGI
- abnormal dendritic cell physiology / MGI
- abnormal cell-mediated immunity / MGI
- abnormal neutrophil physiology / MGI
- abnormal type IV hypersensitivity reaction / MGI
- abnormal leukocyte migration / MGI
- abnormal leukocyte adhesion / MGI
- increased tumor growth/size / MGI
- decreased susceptibility to autoimmune diabetes / MGI
- abnormal regulatory T cell physiology / MGI
- abnormal regulatory T cell number / MGI
- decreased T cell proliferation / MGI
- increased T cell proliferation / MGI
- decreased susceptibility to autoimmune disorder / MGI
- liver/biliary system phenotype / MGI
- immune system phenotype / MGI
- abnormal circulating protein level / MGI
- decreased single-positive T cell number / MGI
- lymph node hypoplasia / MGI
- intermingled spleen red and white pulp / MGI
- impaired neutrophil recruitment / MGI
- abnormal splenic cell ratio / MGI
- small popliteal lymph nodes / MGI
- abnormal cellular extravasation / MGI
- integument phenotype / MGI
- decreased response to antigen / MGI
- impaired leukocyte tethering or rolling / MGI