- decreased locomotor activity / IMPC
C57BL/6NTac-Ttrem1(IMPC)H/H
| Status | Available to order |
| EMMA ID | EM:16938 |
| Citation information | RRID:IMSR_EM:16938 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6NTac-Ttrem1(IMPC)H/H |
| Alternative name | |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Ttrem1(IMPC)H |
| Gene/Transgene symbol | Ttr |
Information from provider
| Provider | Mary Lyon Centre at MRC Harwell |
| Provider affiliation | Mary Lyon Centre at MRC Harwell |
| Genetic information | This mouse line originates from CRISPR zygote microinjection. For further details see the project page at the IMPC portal. |
| Phenotypic information | Potential phenotyping data in the IMPC portal |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- ATTRV30M amyloidosis / Orphanet_85447
- ATTRV122I amyloidosis / Orphanet_85451
- Euthyroid dysprealbuminemic hyperthyroxinemia / Orphanet_597939
IMPC phenotypes (allele matching)
IMPC phenotypes (gene matching)
- decreased locomotor activity / IMPC
MGI phenotypes (gene matching)
- no phenotypic analysis / MGI
- decreased circulating levels of thyroid hormone / MGI
- vision/eye phenotype / MGI
- abnormal circulating protein level / MGI
- abnormal retinol metabolism / MGI
- decreased circulating thyroxine level / MGI
- decreased circulating triiodothyronine level / MGI
- abnormal blood homeostasis / MGI
- abnormal retinol level / MGI
Information on how we integrate external resources can be found here
INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).
