B6.NOD-(D1Mit19-D1Mit14) Chr 17NOD/GhjCnrm
| Status | Available to order |
| EMMA ID | EM:01797 |
| International strain name | B6.NOD-(D1Mit19-D1Mit14) Chr 17NOD/GhjCnrm |
| Alternative name | B6.NOD-C1M-C17S |
| Strain type | Spontaneous |
| Allele/Transgene symbol | Ssial1C57BL/6, |
| Gene/Transgene symbol | Ssial1 |
Information from provider
| Provider | Henri-Jean Garchon |
| Provider affiliation | ER70 CNRS et Unite 125 Inserm |
| Genetic information | C57BL/6 strain double-congenic for the median chromosome 1 of the non-obese diabetic (NOD) strain and for the whole chromosome 17, also substituted from the same strain. |
| Phenotypic information | Sialadenitis and insulitis. |
| Breeding history | The double-congenic strain was selected from an F2 cross between the B6.NOD-C17S (EMMA strain ID EM:01407) and B6.NOD-C1M congenic strains, themselves obtained after 20 generations of backcrossing. |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- An interval tightly linked to but distinct from the H2 complex controls both overt diabetes (Idd16) and chronic experimental autoimmune thyroiditis (Ceat1) in nonobese diabetic mice.;Boulard Olivier, Damotte Diane, Deruytter Nathalie, Fluteau Guy, Carnaud Claude, Garchon Henri-Jean, ;2002;Diabetes;51;2141-7; 12086944
- Mapping non-class II H2-linked loci for type 1 diabetes in nonobese diabetic mice.;Deruytter Nathalie, Boulard Olivier, Garchon Henri-Jean, ;2004;Diabetes;53;3323-7; 15561967
- Identification and mapping to chromosome 1 of a susceptibility locus for periinsulitis in non-obese diabetic mice.;Garchon H J, Bedossa P, Eloy L, Bach J F, ;1991;Nature;353;260-2; 1896073
- Genetic analysis of autoimmune sialadenitis in nonobese diabetic mice: a major susceptibility region on chromosome 1.;Boulard Olivier, Fluteau Guy, Eloy Laure, Damotte Diane, Bedossa Pierre, Garchon Henri-Jean, ;2002;Journal of immunology (Baltimore, Md. : 1950);168;4192-201; 11937580