B6;SJL-Tg(Vps54)#Mm/Cnrm
| Status | Available to order |
| EMMA ID | EM:01826 |
| International strain name | B6;SJL-Tg(Vps54)#Mm/Cnrm |
| Alternative name | Vps54-BAC-tg |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Vps54)#Mm, |
| Gene/Transgene symbol | Tg(Vps54)#Mm |
Information from provider
| Provider | Miriam and Thomas Schmitt-John MEISLER |
| Provider affiliation | Aarhus University, Aarhus, Denmark & GBF, Braunschweig, Germany |
| Genetic information | 163kb BAC with wild-type Vps54 allele complete genomic sequence, including flanking regulatory sequences (68kb upstream and 18kb downstream of Vps54-coding sequences). |
| Phenotypic information | No abnormal phenotype found so far. |
| Breeding history | Male founders were mated with wild-type C57BL/6J females or C57BL/6J females heterozygous for the Vps54-wobbler mutation. F1 offspring are intercrossed. |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- Mutation of Vps54 causes motor neuron disease and defective spermiogenesis in the wobbler mouse.;Schmitt-John Thomas, Drepper Carsten, Mussmann Anke, Hahn Phillip, Kuhlmann Melanie, Thiel Cora, Hafner Martin, Lengeling Andreas, Heimann Peter, Jones Julie M, Meisler Miriam H, Jockusch Harald, ;2005;Nature genetics;37;1213-5; 16244655