STOCK Cdk5rap2an/Ieg

Status

Available to order

EMMA IDEM:00197
International strain nameSTOCK Cdk5rap2an/Ieg
Alternative nameHertwig`s anemia, an
Strain typeInduced Mutant Strains : Radiation-induced
Allele/Transgene symbolCdk5rap2an,
Gene/Transgene symbolCdk5rap2

Information from provider

ProviderDietmar Schlote
Provider affiliationMartin-Luther University, Halle/Wittenberg
Phenotypic informationNormochromic macrocytic type of anemia, lethal within the first post-natal weeks.
ReferencesNone available

Information from EMMA

Archiving centreHelmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany

Disease and phenotype information

MGI allele-associated human disease models

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (allele matching)
  • microcephaly / MGI
  • decreased brain size / MGI
  • abnormal cerebral cortex morphology / MGI
  • decreased body size / MGI
  • premature death / MGI
  • small olfactory bulb / MGI
  • increased neuron apoptosis / MGI
  • abnormal forebrain development / MGI
  • loss of cortex neurons / MGI
  • abnormal mitosis / MGI
  • abnormal embryonic/fetal subventricular zone morphology / MGI
  • thin cerebral cortex / MGI
  • small hippocampus / MGI
  • abnormal mitotic spindle morphology / MGI
  • abnormal neuron proliferation / MGI
  • enlarged brain ventricles / MGI
  • kyphosis / MGI
  • decreased leukocyte cell number / MGI
  • abnormal erythropoiesis / MGI
  • macrocytosis / MGI
  • abnormal spermatogenesis / MGI
  • anemia / MGI
  • reduced fertility / MGI
  • postnatal lethality / MGI
  • decreased germ cell number / MGI
  • abnormal erythrocyte morphology / MGI
  • anisocytosis / MGI
  • macrocytic anemia / MGI
  • premature hair loss / MGI
  • decreased oocyte number / MGI
  • reticulocytopenia / MGI
  • eye opacity / MGI
  • increased ovary adenoma incidence / MGI
  • decreased erythrocyte cell number / MGI

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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