STOCK Prnptm1Cwe Tg(Prnp)941Zbz/Cnrm

Status

Available to order

EMMA IDEM:02028
International strain nameSTOCK Prnptm1Cwe Tg(Prnp)941Zbz/Cnrm
Alternative nameB6,129Sv-Tg941(myc),PrnpZH1/zH1
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolPrnptm1Cwe,
Gene/Transgene symbolPrnp

Information from provider

ProviderAdriano Aguzzi
Provider affiliationUniv.Hosp.Zurich/Inst.Neuropathology
Genetic informationMice expressing PrPC with the human Myc tag, under the control of the endogenous promoter.
Phenotypic informationNone.
ReferencesNone available

Information from EMMA

Archiving centreCNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (allele matching)
  • reduced long term potentiation / MGI
  • abnormal CNS synaptic transmission / MGI
  • abnormal inhibitory postsynaptic potential / MGI
  • abnormal inhibitory postsynaptic currents / MGI
  • behavior/neurological phenotype / MGI
  • decreased brain copper level / MGI
  • tremors / MGI
  • abnormal cerebellum morphology / MGI
  • decreased Purkinje cell number / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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