B6;129S7-Dp(16Dgcr14-Ufd1l)217Bld/Cnrm

Status	Available to order
EMMA ID	EM:02121
International strain name	B6;129S7-Dp(16Dgcr14-Ufd1l)217Bld/Cnrm
Alternative name	Dp(16)1_Bld
Strain type	Targeted Mutant Strains : Other targeted
Allele/Transgene symbol	Dp(16Dgcr14-Ufd1l)217Bld,
Gene/Transgene symbol	Dp(16Dgcr14-Ufd1l)217Bld

Information from provider

Provider	Antonio BALDINI
Provider affiliation	Institute of Genetics and Biophysics (IGB), National Research Council (CNR)
Genetic information	LoxP sites were inserted in trans into genes Es2 and Ufd1l; cre recombination in ES cells generated a chromosomal deletion named Df(16)1_Bld, and a chromosomal duplication named Dp(16)1_Bld. The two mutations were independently established in mice.
Phenotypic information	There are no overt phenotypic abnormalities associated with this duplication, except for behavioral abnormalities (hyperactivity) not yet fully characterized.
Breeding history	Backcrossed to C57BL/6 and then intercrossed; mixed 129 and C57BL/6 (ca. 75% C57BL/6) background.
References	Congenital heart disease in mice deficient for the DiGeorge syndrome region.;Lindsay E A, Botta A, Jurecic V, Carattini-Rivera S, Cheah Y C, Rosenblatt H M, Bradley A, Baldini A, ;1999;Nature;401;379-83; 10517636

Information from EMMA

Archiving centre	CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy

Literature references

Congenital heart disease in mice deficient for the DiGeorge syndrome region.;Lindsay E A, Botta A, Jurecic V, Carattini-Rivera S, Cheah Y C, Rosenblatt H M, Bradley A, Baldini A, ;1999;Nature;401;379-83; 10517636

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Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740^*
Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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