IMPC phenotypes (gene matching)
B6.129-Camk4tm1Gsc/Ieg
| Status | Available to order |
| EMMA ID | EM:02126 |
| Citation information | RRID:IMSR_EM:02126 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129-Camk4tm1Gsc/Ieg |
| Alternative name | CaMKIV flox |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Camk4tm1Gsc |
| Gene/Transgene symbol | Camk4 |
Information from provider
| Provider | Günther Schütz |
| Provider affiliation | Molecular Biology of the Cell I, German Cancer Research Center |
| Genetic information | Exon 3 of the Camk4 gene was flanked by loxP sites. |
| Phenotypic information | None. |
| Breeding history | More than 5 generations of C57BL/6N backcross. Mice will be kept in backcross breeding. |
| References |
|
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Disease and phenotype information
MGI phenotypes (gene matching)
- increased bone mineral density / MGI
- tremors / MGI
- abnormal Purkinje cell morphology / MGI
- decreased Purkinje cell number / MGI
- abnormal female reproductive system morphology / MGI
- abnormal ovarian follicle morphology / MGI
- absent corpus luteum / MGI
- abnormal male reproductive system morphology / MGI
- seminiferous tubule degeneration / MGI
- arrest of spermatogenesis / MGI
- decreased body weight / MGI
- decreased anxiety-related response / MGI
- ataxia / MGI
- hypoactivity / MGI
- impaired coordination / MGI
- reduced long term depression / MGI
- limb grasping / MGI
- abnormal reproductive system physiology / MGI
- reduced female fertility / MGI
- male infertility / MGI
- abnormal gametogenesis / MGI
- abnormal spermiogenesis / MGI
- decreased litter size / MGI
- decreased chemically-elicited antinociception / MGI
- abnormal learning/memory/conditioning / MGI
- premature death / MGI
- abnormal reproductive system morphology / MGI
- no abnormal phenotype detected / MGI
- oligozoospermia / MGI
- decreased vertical activity / MGI
- abnormal excitatory postsynaptic currents / MGI
- abnormal synaptic depression / MGI
- abnormal inhibitory postsynaptic currents / MGI
- abnormal bone remodeling / MGI
- abnormal locomotor activation / MGI
- nervous system phenotype / MGI
- decreased testis weight / MGI
- decreased male germ cell number / MGI
- abnormal behavior / MGI
- decreased osteoclast cell number / MGI
- homeostasis/metabolism phenotype / MGI
- behavior/neurological phenotype / MGI
- teratozoospermia / MGI
- abnormal spermatid morphology / MGI
- abnormal osteoclast differentiation / MGI
- abnormal Purkinje cell dendrite morphology / MGI
- anovulation / MGI
- abnormal sperm flagellum morphology / MGI
- abnormal sperm head morphology / MGI
- polyovular ovarian follicle / MGI
- impaired contextual conditioning behavior / MGI
- impaired cued conditioning behavior / MGI
- impaired conditioned place preference behavior / MGI
- increased bone volume / MGI
Literature references
- Conditional mutagenesis of CamKIV.;Casanova Emilie, Fehsenfeld Sandra, Greiner Erich, Stewart Andrew Francis, Schütz Günther, ;2002;Genesis (New York, N.Y. : 2000);32;161-4; 11857809