B6.129S7-Ess2tm1Bld/Cnrm

Status

Available to order

EMMA IDEM:02204
International strain nameB6.129S7-Ess2tm1Bld/Cnrm
Alternative nameES2
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolEss2tm1Bld,
Gene/Transgene symbolEss2

Information from provider

ProviderAntonio BALDINI
Provider affiliationinstitute of biosciences and technologies, Texas A&M health science center
Genetic informationThe gene was inactivated by homologous recombination in ES cells by replacing a 200bp fragment of exon 4 with an artificial construct comprising: PGK promoter, 2 exons of HPRT minigene, LoxP site, PolII, neo cassette. The targeting generates a null allele.
Phenotypic informationNone in heterozygotes.
References
  • Congenital heart disease in mice deficient for the DiGeorge syndrome region.;Lindsay E A, Botta A, Jurecic V, Carattini-Rivera S, Cheah Y C, Rosenblatt H M, Bradley A, Baldini A, ;1999;Nature;401;379-83; 10517636

Information from EMMA

Archiving centreCNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy

Literature references

  • Congenital heart disease in mice deficient for the DiGeorge syndrome region.;Lindsay E A, Botta A, Jurecic V, Carattini-Rivera S, Cheah Y C, Rosenblatt H M, Bradley A, Baldini A, ;1999;Nature;401;379-83; 10517636

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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