- increased circulating alkaline phosphatase level / IMPC
- limb grasping / IMPC
- increased circulating triglyceride level / IMPC
- increased red blood cell distribution width / IMPC
- preweaning lethality, incomplete penetrance / IMPC
- increased circulating amylase level / IMPC
- decreased exploration in new environment / IMPC
B6;129S5-Elovl6Gt(OST222498)Lex/Orl
Status | Available to order |
EMMA ID | EM:02313 |
Citation information | RRID:IMSR_EM:02313 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
International strain name | B6;129S5-Elovl6Gt(OST222498)Lex/Orl |
Alternative name | LEXKO-129 |
Strain type | Gene-trap |
Allele/Transgene symbol | Elovl6Gt(OST222498)Lex |
Gene/Transgene symbol | Elovl6 |
Information from provider
Provider | Lexicon Genetics, Inc. |
Provider affiliation | Lexicon Pharmaceuticals |
Phenotypic information | Neurological data suggest enhanced motor coordination in the homozygous mutant mice. Serum cholesterol levels were reduced in female (-/-) mice. RT-PCR analysis revealed that the transcript was absent in the homozygous mutant mice. |
References | None available |
Information from EMMA
Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
IMPC phenotypes (gene matching)
MGI phenotypes (allele matching)
- enhanced coordination / MGI
- decreased circulating cholesterol level / MGI
- abnormal liver morphology / MGI
- abnormal lipid homeostasis / MGI
- hepatic steatosis / MGI
- decreased circulating insulin level / MGI
- increased insulin sensitivity / MGI
- increased lean body mass / MGI
- abnormal pancreatic islet morphology / MGI
- abnormal fatty acid level / MGI
- improved glucose tolerance / MGI
- growth/size/body region phenotype / MGI
- decreased circulating leptin level / MGI
- abnormal hepatocyte physiology / MGI
- embryonic lethality, incomplete penetrance / MGI
- decreased fatty acid oxidation / MGI
MGI phenotypes (gene matching)
- abnormal liver morphology / MGI
- abnormal lipid homeostasis / MGI
- hepatic steatosis / MGI
- decreased circulating insulin level / MGI
- increased insulin sensitivity / MGI
- enhanced coordination / MGI
- increased lean body mass / MGI
- decreased circulating cholesterol level / MGI
- abnormal pancreatic islet morphology / MGI
- abnormal fatty acid level / MGI
- improved glucose tolerance / MGI
- growth/size/body region phenotype / MGI
- decreased circulating leptin level / MGI
- abnormal hepatocyte physiology / MGI
- embryonic lethality, incomplete penetrance / MGI
- decreased fatty acid oxidation / MGI
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