- enhanced coordination / MGI
- decreased circulating cholesterol level / MGI
- abnormal liver morphology / MGI
- abnormal lipid homeostasis / MGI
- hepatic steatosis / MGI
- decreased circulating insulin level / MGI
- increased insulin sensitivity / MGI
- increased lean body mass / MGI
- abnormal pancreatic islet morphology / MGI
- abnormal fatty acid level / MGI
- improved glucose tolerance / MGI
- growth/size/body region phenotype / MGI
- decreased circulating leptin level / MGI
- abnormal hepatocyte physiology / MGI
- embryonic lethality, incomplete penetrance / MGI
- decreased fatty acid oxidation / MGI
B6;129S5-Elovl6Gt(OST222498)Lex/Orl
Status | Available to order |
EMMA ID | EM:02313 |
International strain name | B6;129S5-Elovl6Gt(OST222498)Lex/Orl |
Alternative name | LEXKO-129 |
Strain type | Gene-trap |
Allele/Transgene symbol | Elovl6Gt(OST222498)Lex, |
Gene/Transgene symbol | Elovl6 |
Information from provider
Provider | Lexicon Genetics, Inc. |
Provider affiliation | Lexicon Pharmaceuticals |
Phenotypic information | Neurological data suggest enhanced motor coordination in the homozygous mutant mice. Serum cholesterol levels were reduced in female (-/-) mice. RT-PCR analysis revealed that the transcript was absent in the homozygous mutant mice. |
References | None available |
Information from EMMA
Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
MGI phenotypes (allele matching)
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