MGI phenotypes (allele matching)
- decreased B cell number / MGI
B6;129S5-MrasGt(OST108223)Lex/Ieg
| Status | Available to order |
| EMMA ID | EM:02322 |
| International strain name | B6;129S5-MrasGt(OST108223)Lex/Ieg |
| Alternative name | LEXKO-435, MRAS_1 |
| Strain type | Gene-trap |
| Allele/Transgene symbol | MrasGt(OST108223)Lex, |
| Gene/Transgene symbol | Mras |
Information from provider
| Provider | Lexicon Genetics, Inc. |
| Provider affiliation | Lexicon Pharmaceuticals |
| Phenotypic information | Mutation resulted in a decreased mean percentage of peripheral blood B cells in the homozygous mutant mice, as compared to their wild-type (+/+) littermates and historical means. Northern hybridization analysis revealed that the transcript was absent in the homozygous mutant mice. |
| References | None available |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Noonan syndrome / Orphanet_648