IMPC phenotypes (gene matching)
B6;129S5-MrasGt(OST108223)Lex/Ieg
| Status | Available to order |
| EMMA ID | EM:02322 |
| Citation information | RRID:IMSR_EM:02322 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129S5-MrasGt(OST108223)Lex/Ieg |
| Alternative name | LEXKO-435, MRAS_1 |
| Strain type | Gene-trap |
| Allele/Transgene symbol | MrasGt(OST108223)Lex |
| Gene/Transgene symbol | Mras |
Information from provider
| Provider | Lexicon Genetics, Inc. |
| Provider affiliation | Lexicon Pharmaceuticals |
| Phenotypic information | Mutation resulted in a decreased mean percentage of peripheral blood B cells in the homozygous mutant mice, as compared to their wild-type (+/+) littermates and historical means. Northern hybridization analysis revealed that the transcript was absent in the homozygous mutant mice. |
| References | None available |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Noonan syndrome / Orphanet_648
MGI phenotypes (allele matching)
- decreased B cell number / MGI