IMPC phenotypes (gene matching)
- preweaning lethality, complete penetrance / IMPC
B6;129S5-Senp1Gt(OST215108)Lex/Orl
| Status | Available to order |
| EMMA ID | EM:02327 |
| Citation information | RRID:IMSR_EM:02327 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129S5-Senp1Gt(OST215108)Lex/Orl |
| Alternative name | LEXKO-1061 |
| Strain type | Gene-trap |
| Allele/Transgene symbol | Senp1Gt(OST215108)Lex |
| Gene/Transgene symbol | Senp1 |
Information from provider
| Provider | Lexicon Genetics, Inc. |
| Provider affiliation | Lexicon Pharmaceuticals |
| Phenotypic information | Genetic data indicate that the mutation resulted in lethality of the homozygous mutants. The heterozygous mice exhibited enhanced motor coordination during inverted screen testing when compared with their wild-type littermates. Due to lethality, transcript expression analysis was not performed. |
| References | None available |
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
MGI phenotypes (gene matching)
- abnormal erythropoiesis / MGI
- abnormal vascular development / MGI
- abnormal cell death / MGI
- small liver / MGI
- pale liver / MGI
- abnormal liver physiology / MGI
- anemia / MGI
- prenatal lethality / MGI
- abnormal megakaryocyte progenitor cell morphology / MGI
- decreased erythrocyte cell number / MGI
- no phenotypic analysis / MGI
- abnormal vitelline vasculature morphology / MGI
- decreased liver weight / MGI
- pallor / MGI
- enhanced coordination / MGI
- decreased fetal size / MGI
- hematopoietic system phenotype / MGI
- abnormal hemoglobin content / MGI
- abnormal granulocyte differentiation / MGI
- abnormal monocyte differentiation / MGI
- abnormal placental labyrinth vasculature morphology / MGI
- decreased erythroid progenitor cell number / MGI
- postnatal lethality, complete penetrance / MGI
- prenatal lethality, complete penetrance / MGI
- lethality throughout fetal growth and development, complete penetrance / MGI
- lethality throughout fetal growth and development, incomplete penetrance / MGI