MGI phenotypes (allele matching)
B6;129S5-Senp2Gt(OST66117)Lex/Orl
| Status | Available to order |
| EMMA ID | EM:02328 |
| Citation information | RRID:IMSR_EM:02328 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129S5-Senp2Gt(OST66117)Lex/Orl |
| Alternative name | LEXKO-678 |
| Strain type | Gene-trap |
| Allele/Transgene symbol | Senp2Gt(OST66117)Lex |
| Gene/Transgene symbol | Senp2 |
Information from provider
| Provider | Lexicon Genetics, Inc. |
| Provider affiliation | Lexicon Pharmaceuticals |
| Phenotypic information | Genetic data indicate that the mutation resulted in lethality to the homozygous mutants. Female heterozygous mice exhibited a slightly reduced non-fasting blood glucose level. Due to lethality, transcript expression analysis was not performed. |
| References | None available |
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
MGI phenotypes (gene matching)
- abnormal heart development / MGI
- abnormal atrioventricular cushion morphology / MGI
- convulsive seizures / MGI
- audiogenic seizures / MGI
- absent trophoblast giant cells / MGI
- premature death / MGI
- abnormal nervous system electrophysiology / MGI
- thin myocardium / MGI
- small placenta / MGI
- abnormal neuron physiology / MGI
- abnormal brain wave pattern / MGI
- abnormal trophoblast layer morphology / MGI
- abnormal trophoblast giant cell morphology / MGI
- pericardial effusion / MGI
- decreased circulating glucose level / MGI
- abnormal cardiac epithelial to mesenchymal transition / MGI
- atrioventricular block / MGI
- sinus bradycardia / MGI
- prenatal lethality, complete penetrance / MGI
- embryonic lethality during organogenesis, complete penetrance / MGI
- decreased spongiotrophoblast size / MGI