- decreased total body fat amount / IMPC
- polycystic kidney / IMPC
- decreased prepulse inhibition / IMPC
- fibro-osseous lesion / IMPC
- abnormal vertebrae morphology / IMPC
- increased circulating alanine transaminase level / IMPC
- abnormal optic disk morphology / IMPC
- hyperplasia / IMPC
- increased bone mineral density / IMPC
- increased bone mineral content / IMPC
- short tibia / IMPC
- increased circulating aspartate transaminase level / IMPC
B6;129S5-Plekhm1Gt(OST201689)Lex/Orl
Status | Available to order |
EMMA ID | EM:02334 |
Citation information | RRID:IMSR_EM:02334 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
International strain name | B6;129S5-Plekhm1Gt(OST201689)Lex/Orl |
Alternative name | LEXKO-0354 |
Strain type | Gene-trap |
Allele/Transgene symbol | Plekhm1Gt(OST201689)Lex |
Gene/Transgene symbol | Plekhm1 |
Information from provider
Provider | Lexicon Genetics, Inc. |
Provider affiliation | Lexicon Pharmaceuticals |
Phenotypic information | No Notable Phenotype. |
References | None available |
Information from EMMA
Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Intermediate osteopetrosis / Orphanet_210110
IMPC phenotypes (gene matching)
MGI phenotypes (gene matching)
- abnormal osteoclast physiology / MGI
- no abnormal phenotype detected / MGI
- decreased lysosomal enzyme secretion / MGI
- abnormal osteoclast morphology / MGI
- decreased osteoblast cell number / MGI
- decreased bone resorption / MGI
- abnormal lysosome morphology / MGI
- increased bone trabecula number / MGI
- increased trabecular bone mass / MGI
- increased trabecular bone volume / MGI
- decreased bone trabecular spacing / MGI
- decreased bone ossification / MGI
- decreased bone mineralization / MGI
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