IMPC phenotypes (gene matching)
B6;129S5-Ddr1tm1Lex/Orl
| Status | Available to order |
| EMMA ID | EM:02343 |
| Citation information | RRID:IMSR_EM:02343 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129S5-Ddr1tm1Lex/Orl |
| Alternative name | LEXKO-1928 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Ddr1tm1Lex |
| Gene/Transgene symbol | Ddr1 |
Information from provider
| Provider | Lexicon Genetics, Inc. |
| Provider affiliation | Lexicon Pharmaceuticals |
| Phenotypic information | The homozygous mutant mice exhibited increased locomotor activity and a decreased anxiety-related response in the open field when compared with their wild-type littermates and the historical mean. |
| References | None available |
Information from EMMA
| Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
MGI phenotypes (gene matching)
- abnormal cranium morphology / MGI
- abnormal mammary gland development / MGI
- decreased anxiety-related response / MGI
- hyperactivity / MGI
- failure of embryo implantation / MGI
- postnatal growth retardation / MGI
- abnormal lactation / MGI
- abnormal outer ear morphology / MGI
- abnormal bone mineralization / MGI
- increased urine protein level / MGI
- renal/urinary system phenotype / MGI
- homeostasis/metabolism phenotype / MGI
- abnormal podocyte slit diaphragm morphology / MGI
- abnormal mammary gland duct morphology / MGI
- abnormal renal tubule epithelium morphology / MGI
- increased mammary gland epithelial cell proliferation / MGI
- increased renal glomerulus basement membrane thickness / MGI
- erythrocyturia / MGI
- abnormal aorta collagen fibril morphology / MGI