MGI phenotypes (allele matching)
B6;129P2-Grm5tm1Dgen/H
| Status | Available to order |
| EMMA ID | EM:02359 |
| Citation information | RRID:IMSR_EM:02359 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129P2-Grm5tm1Dgen/H |
| Alternative name | DELTAGEN_T797 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Grm5tm1Dgen |
| Gene/Transgene symbol | Grm5 |
Information from provider
| Provider | Deltagen Inc. |
| Provider affiliation | Deltagen Inc. |
| Phenotypic information | Densitometry: fat percent and total tissue mass, low, homozygous females and males, 300 days. Necropsy: body weights, low, homozygous females, 49 days, and homozygous females and males, 300 days. Aging metrics: tendency for low body weight, and low body weight to body length ratio, homozygous females and males. Behavior: Homozygous mutants were impaired on the Rotarod test. Homozygous mutants were significantly different than wild-type control mice on the Metrazol test. Homozygous mutants displayed an increased response latency trend during acute thermal pain tests. |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI phenotypes (gene matching)
- decreased body weight / MGI
- abnormal cued conditioning behavior / MGI
- abnormal spatial learning / MGI
- abnormal contextual conditioning behavior / MGI
- reduced long term potentiation / MGI
- abnormal motor coordination/balance / MGI
- increased thermal nociceptive threshold / MGI
- abnormal cocaine consumption / MGI
- abnormal nociception after inflammation / MGI
- decreased susceptibility to pharmacologically induced seizures / MGI
- increased susceptibility to pharmacologically induced seizures / MGI
- abnormal excitatory postsynaptic potential / MGI
- abnormal locomotor activation / MGI
- abnormal nerve fiber response / MGI
- decreased alcohol consumption / MGI
- behavior/neurological phenotype / MGI
- abnormal latent inhibition of conditioning behavior / MGI
- impaired behavioral response to cocaine / MGI
- decreased total body fat amount / MGI
- abnormal inhibitory learning / MGI