B6;129P2-Grm5tm1Dgen/H

Status

Available to order

EMMA IDEM:02359
International strain nameB6;129P2-Grm5tm1Dgen/H
Alternative nameDELTAGEN_T797
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolGrm5tm1Dgen,
Gene/Transgene symbolGrm5

Information from provider

Provider Deltagen Inc.
Provider affiliationDeltagen Inc.
Phenotypic informationDensitometry: fat percent and total tissue mass, low, homozygous females and males, 300 days. Necropsy: body weights, low, homozygous females, 49 days, and homozygous females and males, 300 days. Aging metrics: tendency for low body weight, and low body weight to body length ratio, homozygous females and males. Behavior: Homozygous mutants were impaired on the Rotarod test. Homozygous mutants were significantly different than wild-type control mice on the Metrazol test. Homozygous mutants displayed an increased response latency trend during acute thermal pain tests.
ReferencesNone available

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

MGI phenotypes (allele matching)
  • decreased body weight / MGI
  • abnormal motor coordination/ balance / MGI
  • increased thermal nociceptive threshold / MGI
  • decreased susceptibility to pharmacologically induced seizures / MGI
  • increased susceptibility to pharmacologically induced seizures / MGI
  • decreased total body fat amount / MGI

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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