IMPC phenotypes (gene matching)
- abnormal retina morphology / IMPC
B6;129P2-Grm8tm1Dgen/H
| Status | Available to order |
| EMMA ID | EM:02360 |
| Citation information | RRID:IMSR_EM:02360 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129P2-Grm8tm1Dgen/H |
| Alternative name | DELTAGEN_T657 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Grm8tm1Dgen |
| Gene/Transgene symbol | Grm8 |
Information from provider
| Provider | Deltagen Inc. |
| Provider affiliation | Deltagen Inc. |
| Phenotypic information | Homozygous mutant animals displayed a statistically significant increase in total distance traveled in the open field test, relative to wild-type animals. Homozygous mutant animals displayed a statistically significant decrease in Prepulse Inhibition (PPI) with a 100dB prepulse. |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI phenotypes (gene matching)
- increased body weight / MGI
- increased anxiety-related response / MGI
- abnormal locomotor behavior / MGI
- decreased exploration in new environment / MGI
- impaired swimming / MGI
- insulin resistance / MGI
- increased percent body fat/body weight / MGI
- decreased physiological sensitivity to xenobiotic / MGI
- decreased prepulse inhibition / MGI