MGI phenotypes (allele matching)
B6;129P2-Pde4btm1Dgen/H
| Status | Available to order |
| EMMA ID | EM:02364 |
| Citation information | RRID:IMSR_EM:02364 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129P2-Pde4btm1Dgen/H |
| Alternative name | DELTAGEN_T1169 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Pde4btm1Dgen |
| Gene/Transgene symbol | Pde4b |
Information from provider
| Provider | Deltagen Inc. |
| Provider affiliation | Deltagen Inc. |
| Phenotypic information | Histopathology: Brain, cerebrum, vacuolization, homozygous females and males. Brain, cerebellum, vacuolization, homozygous females and males. Brain, brainstem, vacuolization, homozygous females and males. Spinal cord, vacuolization, homozygous females and males. |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
| Animals used for archiving | heterozygous C57BL/6J males |
Disease and phenotype information
MGI phenotypes (gene matching)
- abnormal spinal cord morphology / MGI
- decreased anxiety-related response / MGI
- increased exploration in new environment / MGI
- abnormal object recognition memory / MGI
- abnormal learning/memory/conditioning / MGI
- abnormal CNS synaptic transmission / MGI
- increased vertical activity / MGI
- decreased synaptic depression / MGI
- increased post-tetanic potentiation / MGI
- enhanced long term potentiation / MGI
- nervous system phenotype / MGI
- cardiovascular system phenotype / MGI
- behavior/neurological phenotype / MGI
- taste/olfaction phenotype / MGI
- brain vacuoles / MGI
- abnormal spatial working memory / MGI
- decreased tumor necrosis factor secretion / MGI
- impaired neutrophil recruitment / MGI
- impaired neutrophil chemotaxis / MGI
- impaired cued conditioning behavior / MGI
- decreased sensitivity to induced morbidity/mortality / MGI
- abnormal neuron differentiation / MGI
- enhanced learning / MGI