B6.129S7-Septin5tm1Bld/Cnrm

Status

Available to order

EMMA IDEM:02406
International strain nameB6.129S7-Septin5tm1Bld/Cnrm
Alternative namecdc24
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolSeptin5tm1Bld,
Gene/Transgene symbolSept5

Information from provider

ProviderAntonio BALDINI
Provider affiliationinstitute of biosciences and technologies, Texas A&M health science center
Genetic informationAn HPRT-3' targeting cassette containing a loxP site, has been inserted into the endogenous Cdcrel1 (Septin5) gene, so as to replace the GTP binding domain-encoding exons 2-4.
Phenotypic informationNone.
Breeding historyBackcrossed to C57BL/6 inbred mice for 6 generations then maintained by breeding siblings. This breeding is required to maintain a behavioral phenotype.
References
  • Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice.;Lindsay E A, Vitelli F, Su H, Morishima M, Huynh T, Pramparo T, Jurecic V, Ogunrinu G, Sutherland H F, Scambler P J, Bradley A, Baldini A, ;2001;Nature;410;97-101; 11242049

Information from EMMA

Archiving centreCNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy

Literature references

  • Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice.;Lindsay E A, Vitelli F, Su H, Morishima M, Huynh T, Pramparo T, Jurecic V, Ogunrinu G, Sutherland H F, Scambler P J, Bradley A, Baldini A, ;2001;Nature;410;97-101; 11242049

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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