B6.129S7-Septin5tm1Bld/Cnrm
Status | Available to order |
EMMA ID | EM:02406 |
International strain name | B6.129S7-Septin5tm1Bld/Cnrm |
Alternative name | cdc24 |
Strain type | Targeted Mutant Strains : Knock-out |
Allele/Transgene symbol | Septin5tm1Bld, |
Gene/Transgene symbol | Sept5 |
Information from provider
Provider | Antonio BALDINI |
Provider affiliation | institute of biosciences and technologies, Texas A&M health science center |
Genetic information | An HPRT-3' targeting cassette containing a loxP site, has been inserted into the endogenous Cdcrel1 (Septin5) gene, so as to replace the GTP binding domain-encoding exons 2-4. |
Phenotypic information | None. |
Breeding history | Backcrossed to C57BL/6 inbred mice for 6 generations then maintained by breeding siblings. This breeding is required to maintain a behavioral phenotype. |
References |
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Information from EMMA
Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice.;Lindsay E A, Vitelli F, Su H, Morishima M, Huynh T, Pramparo T, Jurecic V, Ogunrinu G, Sutherland H F, Scambler P J, Bradley A, Baldini A, ;2001;Nature;410;97-101; 11242049
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