B6;129S7-Dp(16Dgcr14-Sept5)3Bld/Cnrm
| Status | Available to order |
| EMMA ID | EM:03114 |
| International strain name | B6;129S7-Dp(16Dgcr14-Sept5)3Bld/Cnrm |
| Alternative name | Dp(16)3 (alias 340cdcdup) |
| Strain type | Targeted Mutant Strains : Other targeted |
| Allele/Transgene symbol | Dp(16Dgcr14-Sept5)3Bld, |
| Gene/Transgene symbol | Dp(16Dgcr14-Sept5)3Bld |
Information from provider
| Provider | Antonio BALDINI |
| Provider affiliation | institute of biosciences and technologies, Texas A&M health science center |
| Genetic information | A proximal loxP site replaced part of exon 4 of gene Es2el (Dgcr14). A distal loxP site replaced exons 2-4 of gene Cdcrel1 (Sept5). Cre-mediated recombination was used to generate a tandem duplication of the region spanning Es2el - Cdcrel1 on MMU16. |
| Phenotypic information | No known phenotype in heterozygous or homozygous mutants. |
| Breeding history | Maintained on mixed C57BL/6; 129/SvEv |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- Tbx1 haploinsufficieny in the DiGeorge syndrome region causes aortic arch defects in mice.;Lindsay E A, Vitelli F, Su H, Morishima M, Huynh T, Pramparo T, Jurecic V, Ogunrinu G, Sutherland H F, Scambler P J, Bradley A, Baldini A, ;2001;Nature;410;97-101; 11242049