FVB;129P2-Nf2tm2Gth/Cnrm
| Status | Available to order |
| EMMA ID | EM:00408 |
| International strain name | FVB;129P2-Nf2tm2Gth/Cnrm |
| Alternative name | Nf2F |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Nf2tm2Gth, |
| Gene/Transgene symbol | Nf2 |
Information from provider
| Provider | Anton Berns |
| Provider affiliation | Research - Animal Facility, The Netherlands Cancer Institute |
| Genetic information | Insertion of loxP sequences into intron 2 and 3. |
| Phenotypic information | Conditional Nf2 knock-out, no phenotype. |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
| Animals used for archiving | heterozygous FVB/N, wild-type FVB/N |
| Stage of embryos | 2-cell |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Meningioma / Orphanet_2495
- Neurofibromatosis type 2 / Orphanet_637
Literature references
- Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2.;Giovannini M, Robanus-Maandag E, van der Valk M, Niwa-Kawakita M, Abramowski V, Goutebroze L, Woodruff J M, Berns A, Thomas G, ;2000;Genes & development;14;1617-30; 10887156