| Status | Available to order |
| EMMA ID | EM:04420 |
| International strain name | B6.129S2-Nr2f1tm1Mist/Cnrm |
| Alternative name | COUP-TFI null |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Nr2f1tm1Mist, |
| Gene/Transgene symbol | Nr2f1 |
| Provider | Michele Studer |
| Provider affiliation | Telethon Institute of Genetics and Medicine |
| Genetic information | Targeting construct is derived from 129 DNA. The deletion comprises the 3rd exon and 3'UTR and has been obtained by the Cre-lox technology. A loxP site is maintained. |
| Phenotypic information | Embryonic defects in the central and peripheral nervous system. Lethal at birth. |
| Breeding history | The line is being bred for more than 10 generations on a C57BL/6 strain, but it is not pure yet. |
| References |
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| Homozygous fertile | no |
| Homozygous viable | no |
| Homozygous matings required | no |
| Immunocompromised | no |
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
| Animals used for archiving | heterozygous C57BL/6.129/Sv, wild-type C57BL/6J |
| Stage of embryos | 2-cell |
Orphanet associated rare diseases, based on orthologous gene matching
