B6N.Cg-Tg(Gjc1/EGFP)L43Kwi/Cnrm
| Status | Available to order |
| EMMA ID | EM:04505 |
| International strain name | B6N.Cg-Tg(Gjc1/EGFP)L43Kwi/Cnrm |
| Alternative name | Cx45eGFP |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Gjc1/EGFP)L43Kwi, |
| Gene/Transgene symbol | Tg(Gjc1/EGFP)L43Kwi |
Information from provider
| Provider | Klaus WILLECKE |
| Provider affiliation | Molekulargenetik, Institut fuer Genetik, Universitaet Bonn |
| Genetic information | The Cx45eGFP mouse line expresses a C-terminal fusion protein of connexin 45 (Gjc1) and eGFP, under control of the endogenous connexin 45 promoter using a bacterial artificial chromosome. |
| Phenotypic information | No obvious phenotypes could be detected. |
| Breeding history | The strain was backcrossed with C57BL/6N at least 5 times and is currently bred with C57BL/6N. |
| References |
|
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- C-terminal tagging with eGFP yields new insights into expression of connexin45 but prevents rescue of embryonic lethal connexin45-deficient mice.;von Maltzahn Julia, Kreuzberg Maria M, Matern Gabi, Euwens Carsten, Höher Thorsten, Wörsdörfer Philipp, Willecke Klaus, ;2009;European journal of cell biology;88;481-94; 19473725