B6.Cg-Tg(tetO-Creb*)100Brco/Cnbc
| Status | Available to order |
| EMMA ID | EM:04664 |
| Citation information | RRID:IMSR_EM:04664 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.Cg-Tg(tetO-Creb*)100Brco/Cnbc |
| Alternative name | tetO-ACREB100 |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(tetO-Creb*)100Brco |
| Gene/Transgene symbol | Tg(tetO-Creb*)100Brco |
Information from provider
| Provider | Angel Barco |
| Provider affiliation | Servicio de Experimentación Animal, Instituto de Neurociencias de Alicante |
| Genetic information | Tetracycline regulated expression of the CREB inhibitor, A-CREB. Transgene intended to be used in bitransgenic lines after crossing with tTA or rtTA expressing mice. |
| Phenotypic information | After crossing with CamKIIa-tTA the bitransgenic line showed striatal specific expression. The addiction related phenotypes are described in Front Behav Neurosci. 2009;3:30. |
| Breeding history | Backcrossed to C57BL/6J for more than 15 generations. |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
| Animals used for archiving | heterozygous C57BL/6J, wild-type C57BL/6J |
| Stage of embryos | 8-cell |
Literature references
- Inhibition of cAMP responsive element binding protein in striatal neurons enhances approach and avoidance responses toward morphine--and morphine withdrawal-related cues.;Sanchis-Segura Carles, Jancic Dragana, Jimenez-Minchan Maria, Barco Angel, ;2009;Frontiers in behavioral neuroscience;3;30; 19826619