C57BL/6NTac-Parltm1a(EUCOMM)Hmgu/H
Status | Available to order |
EMMA ID | EM:04692 |
Citation information | RRID:IMSR_EM:04692 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
International strain name | C57BL/6NTac-Parltm1a(EUCOMM)Hmgu/H |
Alternative name | HEPD0513_3_B04 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Parltm1a(EUCOMM)Hmgu |
Gene/Transgene symbol | Parl |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | MRC, Medical Research Council |
Provider affiliation | Mary Lyon Centre at MRC Harwell |
Genetic information | This mouse line originates from EUCOMM ES clone HEPD0513_3_B04. For further details on the construction of this clone see the page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Animals used for archiving | heterozygous C57BL/6NTac males |
Breeding at archiving centre | Chimeras were mated to C57BL/6N Tac USA and maintained on this background thereafter. |
Disease and phenotype information
IMPC phenotypes (allele matching)
MGI phenotypes (gene matching)
- kyphosis / MGI
- abnormal male reproductive system morphology / MGI
- small testis / MGI
- postnatal growth retardation / MGI
- respiratory distress / MGI
- premature death / MGI
- neurodegeneration / MGI
- muscular atrophy / MGI
- cryptorchism / MGI
- no phenotypic analysis / MGI
- increased neuron apoptosis / MGI
- abnormal nervous system physiology / MGI
- spleen atrophy / MGI
- thymus atrophy / MGI
- abnormal uterine environment / MGI
- decreased skeletal muscle mass / MGI
- small epididymis / MGI
- abnormal B cell morphology / MGI
- decreased lymphocyte cell number / MGI
- decreased B cell number / MGI
- decreased double-positive T cell number / MGI
- cachexia / MGI
- abnormal nerve conduction / MGI
- abnormal cell physiology / MGI
- abnormal mitochondrial physiology / MGI
- increased T cell apoptosis / MGI
- decreased skeletal muscle fiber diameter / MGI
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