FVB/N-Tg(E2F1-luc)1Ech/Kctt
| Status | Available to order |
| EMMA ID | EM:04994 |
| Citation information | RRID:IMSR_EM:04994 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | FVB/N-Tg(E2F1-luc)1Ech/Kctt |
| Alternative name | Ef-luc |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(E2F1-luc)1Ech |
| Gene/Transgene symbol | Tg(E2F1-luc)1Ech |
Information from provider
| Provider | Lene Uhrbom |
| Provider affiliation | Department of Neuroscience, Uppsala University |
| Additional owner | Eric C Holland, Departments of Cancer Biology and Genetics, New York, NY , USA |
| Genetic information | Transgenic construct: pE2F1-luciferase. |
| Phenotypic information | Expression of firefly luciferase is regulated by the E2F1 promoter, allowing tumor cell development to be followed by luciferase imaging. |
| Breeding history | The founder mouse was crossed with FVB/N and subsequently intercrossed. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Karolinska Institutet, Stockholm, Sweden |
| Animals used for archiving | homozygous males, wild-type FVB/N females |
| Breeding at archiving centre | No breeding |
| Stage of embryos | 2-cell |
Literature references
- Dissecting tumor maintenance requirements using bioluminescence imaging of cell proliferation in a mouse glioma model.;Uhrbom Lene, Nerio Edward, Holland Eric C, ;2004;Nature medicine;10;1257-60; 15502845