- no phenotypic analysis / MGI
C57BL/6NTac-Gt(ROSA)26Sortm2(CAG-flpo,-EYFP)Ics/Ics
Status | Available to order |
EMMA ID | EM:05490 |
International strain name | C57BL/6NTac-Gt(ROSA)26Sortm2(CAG-flpo,-EYFP)Ics/Ics |
Alternative name | Gt(ROSA)26Sor |
Strain type | Targeted Mutant Strains : Other targeted |
Allele/Transgene symbol | Gt(ROSA)26Sortm2(CAG-flpo, -EYFP)Ics |
Gene/Transgene symbol | Gt(ROSA)26Sor |
Information from provider
Provider | ICS |
Provider affiliation | Institut Clinique de la Souris |
Genetic information | Targeting construct is derived from C57BL/6N DNA. The pCAG promoter followed by the FlpO recombinase fused to T2A and eYFP sequences was inserted into the Gt(ROSA)26Sor locus. |
Phenotypic information | Sublethal phenotype for heterozygous females (10%) Heterozygous females are hypofertile with some death observed during pregnancy or right after giving birth. |
Breeding history | Colony is maintained by heterozygous male x C57BL/6N wild-type female breeding, |
References |
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Homozygous fertile | not known |
Homozygous viable | yes |
Homozygous matings required | no |
Immunocompromised | no |
Information from EMMA
Archiving centre | ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France |
Disease and phenotype information
MGI phenotypes (allele matching)
Literature references
- Highly-efficient, fluorescent, locus directed cre and FlpO deleter mice on a pure C57BL/6N genetic background.;Birling Marie-Christine, Dierich Andrée, Jacquot Sylvie, Hérault Yann, Pavlovic Guillaume, ;2012;Genesis (New York, N.Y. : 2000);50;482-9; 22121025
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