MGI phenotypes (gene matching)
- no phenotypic analysis / MGI
C57BL/6N-Tmem45btm1.2Arte/Ieg
| Status | Available to order |
| EMMA ID | EM:05498 |
| Citation information | RRID:IMSR_EM:05498 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Tmem45btm1.2Arte/Ieg |
| Alternative name | TMEM45B KO conv |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Tmem45btm1.2 |
| Gene/Transgene symbol | Tmem45b |
Information from provider
| Provider | Helmholtz Zentrum Muenchen |
| Provider affiliation | Institute of Experimental Genetics, Helmholtz Zentrum Muenchen German Research Center for Environmental Health (GmbH) |
| Genetic information | Exons 3-5 have been flanked by loxP sites, as their genetic ablation should result in loss of function by deletion of most of the open reading frame and generation of a frameshift (see EMMA strain EM:05499). The constitutive knock-out mutation has been obtained by in vivo cre recombinase-mediated deletion. |
| Phenotypic information | TO BE PROVIDED |
| Breeding history | Targeting performed in C57BL/6N ES cells and confirmed by Southern blotting. Tmem45b floxed mice were crossed to C57BL/6N-Gt(ROSA)26Sortm16(cre)Arte mice to obtain the Tmem45b null allele. Maintained on C57BL/6N background. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
| Animals used for archiving | heterozygous C57BL/6NTac males, wild-type C57BL/6N females |
| Stage of embryos | 2-cell |