B6N(Cg)-Gt(ROSA)26Sortm1(MMTV-ANKRD30A,-luc)Arte/Ieg
Status | Available to order |
EMMA ID | EM:05512 |
International strain name | B6N(Cg)-Gt(ROSA)26Sortm1(MMTV-ANKRD30A,-luc)Arte/Ieg |
Alternative name | NYBR1 TG targ |
Strain type | Targeted Mutant Strains : Knock-in |
Allele/Transgene symbol | Gt(ROSA)26Sortm(MMTV-ANKRD30A,-luc)Arte |
Gene/Transgene symbol | Gt(ROSA)26Sor |
Information from provider
Provider | Helmholtz Zentrum Muenchen |
Provider affiliation | Institute of Experimental Genetics, Helmholtz Zentrum Muenchen German Research Center for Environmental Health (GmbH) |
Genetic information | Targeted insertion of a MMTV-hNYBR1 transgene into the Gt(ROSA)26Sor locus by recombination-mediated cassette exchange (RMCE). The inserted construct contains an MMTV promoter fragment, a human ANKRD30A (or Breast Cancer Antigen NY-BR-1, https://www.genecards.org/cgi-bin/carddisp.pl?gene=ANKRD30A) cDNA, an IRES-luciferase sequence and a synthetic polyadenylation signal. Termination of endogenous Gt(ROSA)26Sor transcription by a neomycin-resistance cassette. |
Phenotypic information | TO BE PROVIDED |
Breeding history | Maintained on C57BL/6N background. |
References | None available |
Homozygous fertile | not known |
Homozygous viable | not known |
Homozygous matings required | not known |
Immunocompromised | not known |
Information from EMMA
Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
Animals used for archiving | heterozygous C57BL/6NTac, wild-type C57BL/6N |
Stage of embryos | 2-cell |
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