STOCK Gt(ROSA)26Sortm1.1(Otx2)Daac/Cnrm
Status | Available to order |
EMMA ID | EM:05634 |
International strain name | STOCK Gt(ROSA)26Sortm1.1(Otx2)Daac/Cnrm |
Alternative name | R26-bOtx2 |
Strain type | Targeted Mutant Strains : Knock-in |
Allele/Transgene symbol | Gt(ROSA)26Sortm1.1(Otx2)Daac, |
Gene/Transgene symbol | Gt(ROSA)26Sor |
Information from provider
Provider | Antonio Simeone |
Provider affiliation | Ceinge Biotecnologie Avanzate |
Genetic information | Replacement of Gt(ROSA)26Sor gene with Otx2 cDNA by homologous recombination. |
Phenotypic information | No phenotype. |
Breeding history | Targeted mutation was introduced in E14 ES cells. Mice were always maintained in a mixed C57BL/6 and DBA/2 genetic background. |
References |
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Homozygous fertile | yes |
Homozygous viable | yes |
Homozygous matings required | yes |
Immunocompromised | no |
Information from EMMA
Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Literature references
- Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP.;Di Salvio Michela, Di Giovannantonio Luca Giovanni, Acampora Dario, Prosperi Raffaele, Omodei Daniela, Prakash Nilima, Wurst Wolfgang, Simeone Antonio, ;2010;Nature neuroscience;13;1481-8; 21057506
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