STOCK Otx2tm5.1Asim/Cnrm
Status | Available to order |
EMMA ID | EM:05642 |
International strain name | STOCK Otx2tm5.1Asim/Cnrm |
Alternative name | Otx2-Δ5' |
Strain type | Targeted Mutant Strains : Other targeted |
Allele/Transgene symbol | Otx1tm5.1Asim, |
Gene/Transgene symbol | Otx2 |
Information from provider
Provider | Antonio Simeone |
Provider affiliation | Ceinge Biotecnologie Avanzate |
Genetic information | Deletion affecting Otx2 distal isoforms. |
Phenotypic information | Homozygous embryos exhibited severe head abnormalities. |
References | None available |
Homozygous fertile | no |
Homozygous viable | no |
Homozygous matings required | no |
Immunocompromised | no |
Information from EMMA
Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Combined pituitary hormone deficiencies, genetic forms / Orphanet_95494
- Butterfly-shaped pigment dystrophy / Orphanet_99001
- Colobomatous microphthalmia / Orphanet_98938
- Nanophthalmos / Orphanet_35612
- Syndromic microphthalmia type 5 / Orphanet_178364
- Septo-optic dysplasia spectrum / Orphanet_3157
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