MGI phenotypes (allele matching)
B6.129S7-Vax2tm1Sba/Cnrm
| Status | Available to order |
| EMMA ID | EM:00584 |
| International strain name | B6.129S7-Vax2tm1Sba/Cnrm |
| Alternative name | 129/C57BL6/Vax2-/- |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Vax2tm1Sba, |
| Gene/Transgene symbol | Vax2 |
Information from provider
| Provider | Sandro Banfi |
| Provider affiliation | Telethon Institute of Genetics and Medicine (TIGEM) |
| Genetic information | The mutation has been obtained by homologous recombination by deleting the second coding exon of the Vax2 gene. |
| Phenotypic information | Alteration of the eye, dorso-ventral axis, incompletely penetrant eye coloboma. |
| References |
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Information from EMMA
| Archiving centre | CNR, Consiglio Nazionale delle Ricerche, Monterotondo, Italy |
Disease and phenotype information
Literature references
- Vax2 inactivation in mouse determines alteration of the eye dorsal-ventral axis, misrouting of the optic fibres and eye coloboma.;Barbieri Anna Maria, Broccoli Vania, Bovolenta Paola, Alfano Giovanna, Marchitiello Anna, Mocchetti Cristina, Crippa Luca, Bulfone Alessandro, Marigo Valeria, Ballabio Andrea, Banfi Sandro, ;2002;Development (Cambridge, England);129;805-13; 11830579