C57BL/6NTac-Wbp2tm2a(EUCOMM)Wtsi/WtsiH
Status | Available to order |
EMMA ID | EM:05860 |
International strain name | C57BL/6NTac-Wbp2tm2a(EUCOMM)Wtsi/WtsiH |
Alternative name | EPD0037_2_D06 |
Strain type | Targeted Mutant Strains |
Allele/Transgene symbol | Wbp2tm2a(EUCOMM)Wtsi, |
Gene/Transgene symbol | Wbp2 |
Disclaimer | Please note that for EUCOMM and KOMP-CSD mice supplied to the scientific community by INFRAFRONTIER/EMMA:
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Information from provider
Provider | Wellcome Trust Sanger Institute |
Provider affiliation | Wellcome Trust Sanger Institute |
Genetic information | This mouse line originates from EUCOMM ES clone EPD0037_2_D06. For further details on the construction of this clone see the page at the IMPC portal. |
Phenotypic information | Potential phenotyping data in the IMPC portal |
References | None available |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Animals used for archiving | homozygous C57BL/6NTac |
Breeding at archiving centre | Received as frozen sperm. |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Autosomal recessive non-syndromic sensorineural deafness type DFNB / Orphanet_90636
IMPC phenotypes (allele matching)
MGI phenotypes (allele matching)
- abnormal organ of Corti morphology / MGI
- abnormal distortion product otoacoustic emission / MGI
- sensorineural hearing loss / MGI
- abnormal cochlear IHC afferent innervation pattern / MGI
- abnormal cochlear OHC afferent innervation pattern / MGI
- hearing/vestibular/ear phenotype / MGI
- abnormal auditory summating potential / MGI
- decreased circulating amylase level / MGI
- abnormal auditory brainstem response waveform shape / MGI
- increased or absent threshold for auditory brainstem response / MGI
- hyperactivity / MGI
- abnormal behavior / MGI
- decreased circulating serum albumin level / MGI
- absent pinna reflex / MGI
- decreased circulating fructosamine level / MGI
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