B6.129-Tg(Tie1-cre)9Ref/Kieg
| Status | Available to order |
| EMMA ID | EM:00606 |
| Citation information | RRID:IMSR_EM:00606 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129-Tg(Tie1-cre)9Ref/Kieg |
| Alternative name | Tie1-Cre |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Tie1-cre)9Ref |
| Gene/Transgene symbol | Tg(Tie1-cre)9Ref |
Information from provider
| Provider | Erika Gustafsson |
| Provider affiliation | Department of Experimental Pathology |
| Genetic information | The expression construct contains a floxed neomycin cassette, a 1.15 kb HindIII-ApaI fragment of the mouse Tie1 promoter (Iljin et al. 1999), and an EcoRI-XhoI fragment of pMC1-Cre (Gu et al. 1993) containing a nuclear localization signal, cre recombinase cDNA and a pA+ signal. For a more detailed description of the generation, see reference. |
| Phenotypic information | No defects observed |
| References |
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Information from EMMA
| Archiving centre | Karolinska Institutet, Stockholm, Sweden |
Literature references
- Tie-1-directed expression of Cre recombinase in endothelial cells of embryoid bodies and transgenic mice.;Gustafsson E, Brakebusch C, Hietanen K, Fässler R, ;2001;Journal of cell science;114;671-6; 11171372
- Investigating the effects of a cryptic splice site in the En2 splice acceptor sequence used in the IKMC knockout-first alleles.;Nair Prerna, Steel Karen P, Lewis Morag A, ;2024;Mammalian genome : official journal of the International Mammalian Genome Society;35;633-644; 39354111